Virus vs Bacteria!

Zeldovich, Lina.  The Living Medicine: How a Miraculous Healing Therapy was Nearly Lost -- 

         and  Why It Will Save Humanity When Antibiotics Fail.  New York: St. Martin's Press, 

        2024.  ISBN: 9781250283382

 

So what is a living medicine? And why would you want to take it?  In this title, it is a phage or more properly a bacteriophage which is a virus that attacks specific bacteria.  They are found anywhere there is bacteria and they "eat" that bacteria and leave other bacteria alone.  Plus they can work when antibiotics fail.  That is part of the point Lina Zeldovich  is making in The Living Medicine, part medical discovery, part historical account and part biography.

 

Lina Zeldovich opens the book with a description of the present day and the problem with antibiotic resistant bacteria.  She then jumps back to World War I and the search for cures to infectious diseases such as dysentery, cholera, and typhus.  They had vaccines, but those took time to prepare.  Giorgi Eliava was a doctor in Georgia (the country) who was working on cholera in Tbilisi when he accidentily discovered phages that were eating cholera bacteria in the samples he was testing, not that his microscope was powerful enough to see them, but he could see the results.  Around the same time Felix d'Herelle at the Pasteur Institute in Paris encountered similar action in regard to dysentery.  After the war Eliaya and d'Herelle got together in Paris and worked on refining the process of manufacturing phages that would kill various infectious diseases.  In the 1920's and 1930's they worked on creating institutes in Tbilisi (Soviet Republic of Georgia) and Paris.  Other folks started their own businesses doing the same in other parts of the world.  But capitalism killed phages in the US since there was no governmental regulation and the public did not trust the manufactures.  In the Soviet Union, phage research continued under government scrutiny and sort of thrived.  Phages played a part in saving Stalingrad from the German invasion by preventing a cholera outbreak.  But then there came the end of the Soviet Union and disintegration of many institutions which included the library of phages collected from all over the Soviet Union.  But with the rise of antibiotic resistant bacteria, scientists and the FDA in the United States are more willing to try other means.  So do not be surprised if you get treated with phages in the near future. 

If you are looking for an engaging book dealing with history, science, and medicine, pick up Lina Zeldovich's The Living Medicine!  Your time will be rewarded!